https://www.ceesdekker.net Secrets
https://www.ceesdekker.net Secrets
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‘Sure, that is definitely about correct. I seek out a Actual physical knowledge of Organic units inside a base-up way. I do think you can distinguish 3 strains of analysis in my group at the moment. The primary fears chromosome structure: How would you get a metre-extended DNA polymer folded and organised in this type of microscopic mobile? Now we have created visualisation tactics that allow for us to study how, as an example, SMC proteins loop DNA (movie on Youtube) so that you can Construct up chromosomes.
Our group experiments bacterial mobile division which is aiming to constitute a ‘bottom up biology’ in artificial cells that could autonomously divide. Our principal interest lies in mobile division, chromatin framework, and spatial Handle.
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Considering that 2000, Dekker has shifted the key concentration of his work in direction of biophysics wherever he studies the Homes of solitary biomolecules and cells utilizing the tools of nanotechnology. This transformation of subject was pushed by his fascination with the outstanding working of Organic molecular buildings, and from the prolonged-expression standpoint that many intriguing discoveries might be predicted During this industry.[five] Current lines of study in his biophysics group are within the areas of:[6]
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial at any time research of your dynamics DNA supercoils and the discovery of supercoil hopping
Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of an individual wire bridging two electrodes
All parameters were being exactly the same for each panel In this particular movie, aside from the First placement of your 6hb rod (revealed in blue) on the nanopore. Simulations that terminated early as a result of translocation on the rod from the pore are marked by a gray history.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim from the pore is highlighted in purple, as well as a 3D rendering of your motion of your DNA rod is displayed.
What if, instead of working with traditional top-down silicon electronics, transistors may very well be developed from The underside up employing single organic and natural molecules as the switching things? This idea, which turned the basis of nowadays’s field of molecular electronics, initially emerged within the seventies.
There was a person problem although — we did not observe any measurable electrical conduction from The only polymer molecules. We concluded that at The only-molecule stage, conducting polymers have been essentially not these types of terrific conductors, which was rather disappointing. We Therefore broadened our check out to try to discover a lot more promising molecules.
‘The concept there is such a point for a commencing, a big bang, is previously a fascinating signpost to consider that there was a creator. But a lot more normally, and on The premise of pure rationality, I also get there in a Christian interpretation of truth. An atheistic worldview is a naturalistic worldview: fundamentally, you'll find only atoms and normal forces that we could evaluate.
2006, 1st demonstration of molecular sorting inside of a lab on a chip employing biomotors; discovery of nanobubbles in good-state nanopores; and 1st estimate of electrokinetic Electrical power conversion inside a nanofluidic channel
Enable’s first look back in the meanwhile any time you https://www.ceesdekker.net made a decision to change your concentrate from superconductivity and nanotubes to biology at the end of the nineties.
2013, managed shaping of Reside bacterial cells into arbitrary styles; and discovery of spontaneous fluctuations inside the handedness of histone tetrasomes